The present research was undertaken to evaluate of soybean hybrids environmental interaction and adaptability on Mediterranean region conditions. Seven advanced (F7) soybean lines selected from the Kunitz x SS-201 and Kunitz x Bert cross populations based on earliness and yield characteristics in the preliminary trials and three soybean varieties (Bravo, Nova and Arisoy) were tested in the trial in four replications in 2017 and 2018 in accordance with the RCBD. The analysis of variance revealed significant variations for all characters. According to results, the yield of lines and varieties 2017 and 2018 varied from 2.87-4,47 t ha-1 and 2.61-3.90 t ha-1 respectively and KS-39 advanced soybean line had the highest grain yield in terms of two years average. The number of flowering days varied between 32.50 days and 36.75 days according to the two-year averages, and the KS-12 genotype was the earliest flowering genotype. The lines KS-10 (103.38) and KS-12 (103.50) came to the fore as the genotypes with the earliest maturation days. With this study, it has been concluded that promising genotypes can be obtained in regions dominated by the Mediterranean climate zone (especially the Aegean coastline), and soybean cultivation can be done in double crop agriculture within the cropping system.