Main Article Content
The purpose of this study was to observe the efficacy of nano-hydroxyapatite / collagen (nHAC) for lumbar intervertebral fusion in the treatment of lumbar instability method of care. In this study, a biomimetic method was used to prepare nano-phase hydroxyapatite / collagen composites and used in the clinic. Lumbar pedicle screw fixation system was performed on 30 patients (27 segments) with lumbar vertebra instability who were treated in our hospital from January 2018 to December 2019, assisted by nHAC intervertebral implantation and fusion of vertebral bodies through observe and evaluate the healing of patients; thirty patients with lumbar instability were given adequate psychological care, preoperative training, strict postoperative observation, prevention of complications, and rehabilitation training. With the results show that nHAC is similar to natural bone in composition and microstructure, while patients contain no high fever, exudation and immune rejection after implantation, also bone repair is good. All patients were followed up, with an average follow-up of 14.2 months after surgery. According to the JOA evaluation criteria, 16 cases were excellent, 8 cases were good, and 6 cases were fair with excellent rate is 80%. It is concluded that nHAC is one of the excellent bone repair materials while lumbar interbody fusion using nHAC is an ideal treatment for lumbar instability.